Take the A5 or the A67 to the Darmstadt-Mitte exit. From there, continue straight on in the direction of the city center. When entering the city center tunnel, first turn right, then left in the tunnel and follow the City-Ring. Turn left again at the next traffic light. Continue on the City-Ring, pass the Darmstadtium and turn left until you reach the entrance to the parking garage »Schlossgarage/Karolinenplatz«.